Oligonucleotide Probes

Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin.

Also Known As:

Probe, Oligonucleotide; Probes, Oligodeoxyribonucleotide; Probes, Oligonucleotide; Probes, Oligoribonucleotide; Oligodeoxyribonucleotide Probes; Oligonucleotide Probe; Oligoribonucleotide Probes

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleic Acids: 11752
  - Nucleic Acid Probes: 53
    - Oligonucleotide Probes: 641
Chemical Actions and Uses
- Pharmacologic Actions: 160
  - Diagnostic Uses of Chemicals
    - Molecular Probes: 819
      - Nucleic Acid Probes: 53
        Oligonucleotide Probes: 641
- Specialty Uses of Chemicals
  - Laboratory Chemicals: 1
    - Molecular Probes: 819
      - Nucleic Acid Probes: 53
        Oligonucleotide Probes: 641

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